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Danaher Corporation Senior Associate or Scientist, Protein Reagent Development in Bothell, Washington

Job Title: Senior Associate or Scientist, Protein Reagent Development

Job Location: Bothell

Date Written: March 31, 2021

Written By: Samuel Li

Job Profile (Level-Job Family): P3-Professional


Cepheid is a leading molecular diagnostics company that is an operating company within Danaher Corporation's Diagnostics platform. Cepheid is dedicated to improving healthcare by developing, manufacturing, and marketing accurate yet easy-to-use molecular systems and tests. By automating highly complex and time-consuming manual procedures, the company's solutions deliver a better way for institutions of any size to perform sophisticated molecular diagnostic testing for organisms and genetic-based diseases. Through its strong molecular biology capabilities, the company is focusing on those applications where accurate, rapid, and actionable test results are needed most, such as managing infectious diseases and cancer.

The successful applicant will work at the Department of Protein Reagent Development and Production to develop and produce protein reagents, with focus on engineering and manufacturing recombinant proteins including recombinant enzymes. He/She will contribute to multiple phases of bioprocess development and production of enzymes and proteins. The position level depends on the experience and responsibilities.


  • Develop robust and effective processes for protein purification and production.

  • Collaborate with the upstream process development to clarify and process batch production lots of protein expression cultures.

  • Produce recombinant enzymes and protein reagents under GMP environment.

  • Characterize recombinant protein biochemically and functionally.

  • Actively collaborate with other functions such as Bioanalytical, QA and QC.

  • Evaluate and implement new technologies for protein downstream process development and manufacturing.

  • Maintain data records, generate SOP, development, technical reports and production batch record.

  • Be motivated to perform in a cooperative cross functional setting to maximize the efficiency of the protein reagent program.


  • Complete all assigned and required training satisfactorily and on time

  • For people managers, ensure your associates attend and complete all required trainings satisfactorily and on time.


Education and Experience (in years):

  • BS or MS in Biochemistry or related field

  • 5+ years (for BS) and 3+ years (for MS) of relevant industry experience in biologics development and/or manufacturing facility environment are minimal

Knowledge and skills:

  • Demonstrated success in recombinant protein purification in E. coli and mammalian expression systems.

  • Knowledge of protein production in E. coli and mammalian expression systems a plus.

  • Excellent track record for protein purification process development, protein analysis and characterization,

  • Experience in protein purification development and production under GLPs necessary and knowledge and experience with cGMP setting desirable.

  • Strong analytical and problem-solving skills are necessary.

  • Demonstrated ability to collaborate effectively with cross functional teams to achieve objectives.

  • Excellent communication, inter-personal and organizational skills are required.

Physical requirements/abilities:

  • Must be able to lift 40 lbs.

The statements in this description represent typical elements, criteria and general work performed. They are not intended to be an exhaustive list of all responsibilities, duties, and skills for this job.

Danaher Corporation and all Danaher Companies are equal opportunity employers that evaluate qualified applicants without regard to race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. The “EEO is the Law” poster is available here (http://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf) .

Operating Company: Cepheid