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Danaher Corporation Sr. Scientist, Upstream Biomanufacturing in Madison, Wisconsin

Aldevron is an industry pioneer with a core competency in manufacturing for gene and cell therapy. We supply high-quality plasmid DNA, mRNA and proteins to our clients, who are breaking new ground on the world’s most important and challenging solutions to benefit us all. We're looking for innovative, forward-thinking individuals who share our goals of advancing science and making an impact on the world.

Aldevron is proud to work alongside a community of nine fellow Danaher Life Sciences companies. Together, we’re pioneering the future of science and medicine, developing products that enable researchers in the fight to save lives.

The Senior Scientist, Upstream BioManufacturing has a strong working knowledge of microbial systems, bacterial metabolism, protein expression and current bioprocessing technologies. This individual must possess a proven track record of working in a microbial fermentation lab/pilot scale and have the ability to develop and write standard operating procedures. This role requires a critical thinker with a continuous improvement mind-set and the ability to operate and troubleshoot fermentor operations. The Senior Scientist, US BioMFG is primarily responsible for the execution of 1-L to 1000-L scale microbial fermentations. This position requires excellent laboratory skills, great attention to detail and excellent documentation practices.

Responsibilities:

  • Lead the execution, partnering with team members, of 1 L – 1000 L scale fermentations within manufacturing setting.

  • Actively engage with personnel from Process Development and Process Engineering to improve process robustness and performance.

  • Execute project plans according to all specifications, including timeline and budget

  • Create/modify SOPs and Batch Record forms for fermentation processes

  • Assist Process Engineers in the technical transfer of fermentation processes from research grade to the GMP manufacturing team

  • Perform within ISO regulated environment

Qualifications:

Experience:

  • Has extensive, hands-on experience with microbial fermentation methods within a Manufacturing environment.

  • Operating bench-top, lab-, and pilot-scale bioreactors

  • Batch and fed-batch fermentation processes

  • Utilizing large scale harvest equipment (e.g.- continuous flow centrifugation)

  • Experience with microbial fermentation to express recombinant proteins

  • Experience working within a Quality Management System, familiarity with ISO certified labs and GMP working environments a plus

  • Previous experience with St. steel bioreactors is a plus

Education:

  • Degree in biology, molecular biology, biochemistry, chemistry or a closely related field

  • Bachelor’s degree and 10+ years of relevant work experience (in Manufacturing)

  • Master’s degree and 6+ years of relevant work experience (in Manufacturing)

  • Ph.D and 2+ years of relevant work experience (in Manufacturing)

When you join us, you’ll also be joining Danaher’s global organization, where 80,000 people wake up every day determined to help our customers win. As an associate, you’ll try new things, work hard, and advance your skills with guidance from dedicated leaders, all with the support of powerful Danaher Business System (https://www.danaher.com/how-we-work/danaher-business-system) tools and the stability of a tested organization.

Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. We value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes.The EEO posters are available here (https://www.dol.gov/agencies/ofccp/posters) .We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us at applyassistance@danaher.com to request accommodation. If you’ve ever wondered what’s within you, there’s no better time to find out.

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