Danaher Corporation Scientist, Process Transfer and Development - Upstream in Marlborough, Massachusetts
Scientist, Process Transfer and Development, upstream
Help us improve access to life-changing therapies that can transform human health.
We are Cytiva, a global provider of technologies and services that advance and accelerate the development and manufacture of therapeutics. Formerly part of GE Healthcare, we have a rich heritage tracing back hundreds of years, and a fresh beginning since 2020.
Our customers undertake life-saving activities. These range from fundamental biological research to developing innovative vaccines, biologic drugs, and novel cell and gene therapies. Our job is to supply the tools and services - the pots, pans, soups, and sauces so to speak - they need to work better, faster and safer, leading to better patient outcomes.
We are looking for a Scientist to work with our expert Upstream Process Transfer and Development team in Marlborough, Massachusetts. Do you have a passion for Biotechnology? Then we would love to hear from you.
What you’ll do:
- Work within a team of Scientists in the Process Transfer and Development (PTD) team. This department owns the responsibility for all Upstream (Cell Culture and Fermentation) activities within the Fast Track - Biomanufacturing (FTBM) organization.
Upstream process development.
Internal and external technical transfer of Upstream processes.
Conventional and single-use manufacturing suite design support.
Marketing support and evaluation/development of new Upstream technologies and devices.
Key responsibilities/essential functions and behaviors:
Action oriented: able to help build and develop a cohesive team unit.
Demonstrate effective written and verbal communication skills and provide instruction to others when required.
Subject matter expertise on all Upstream activities (Cell Culture and Fermentation)
Ability to work within ISO 5/6/7/8 clean room environments.
Support operations of standard -GMP and non-cGMP Biomanufacturing equipment, including;
pH/conductivity meters, single use mixing tanks (XDM’s), tubing fusers/sealers, filter integrity testers, cell counters, metabolite analyzers, peristaltic pumps, balances and biosafety cabinets (BSC).
Supports Cell Culture operations and equipment in a cleanroom environment, including;
Incubators, Wave Reactors, Single Use Bioreactors (XDR), Ambr 15 System, NOVA Flex, NOVA Flex 2, Vi-Cell and Vi-Cell Blue
Work with cross-functional teams on the implementation of process improvement initiatives to increase quality and productivity levels.
Perform investigations and support closure of c-GMP process deviations within the quality systems.
Monitor and escalate discrepancies with QA and EHS procedures and policies as required.
Demonstrate an ability to multi-task and manage multiple projects independently.
Maintain a safe work environment for self and staff.
Qualifications / Who you are:
An B.S./M.S./Ph.D. degree in Biology, Biochemistry, Biomanufacturing or Chemical Engineering
5+ years relevant work experience
Subject Matter Expertise of Upstream processing.
Experience developing, scaling and transferring the following Upstream unit operations: thaw, expansion, production bioreactor, cell harvest & clarification.
Demonstrated ability to lead and influence in a collaborative, matrixed, and customer focused environment.
Ability to communicate expectations and hold team accountable to all production, safety and quality requirements.
Demonstrate ability to give direction to others.
Ability to provide instructions regarding policies and procedures.
Demonstrates ability to work in a rapidly changing climate and reacts well to change.
Demonstrates strong attention to detail and have quality-minded work habits
Reliable, dependable, and organized
Able to recognize problems developing, not just occurring
Ability to work additional hours as needed to support production and development
Demonstrates effective written and verbal communication skills
Upstream Biologics Processes (Cell Culture and Fermentation) development and manufacturing
Technical transfer of Upstream processes
Scale-up/scale-down of Upstream processes
cGMP manufacturing support
cGMP document preparation support
Proficiency in Microsoft Office
Media and Feed Studies
Harvest and Clarification Studies
Cytiva/Xcellerex XDM Bioreactor system experience a plus
Amber system experience a plus
Upstream single-use technologies
Who we are:
Whatever your role, we bring purpose and challenge into our everyday work. If you are driven to make the world a better place thanks to science and medicine, you’ll feel right at home here. If you’re flexible, curious and relentless, you’ll belong. If you are excited about a global culture, this can be the place to further your career.
Want to know more? Experience life at Cytiva on our Careers website, Instagram channel and LinkedIn page
Cytiva is a 3.3 billion USD global life sciences leader with nearly 7000 associates across 40 countries who are dedicated to our mission to advance and accelerate therapeutics. As a trusted partner to customers that range in scale and scope, Cytiva brings efficiencies to research and manufacturing workflows, ensuring the development, manufacture and delivery of transformative medicines to patients.
Cytiva is part of the Danaher family of companies, a global science and technology innovator committed to helping customers solve complex challenges and improving quality of life around the world.
Danaher Corporation and all Danaher Companies are equal opportunity employers that evaluate qualified applicants without regard to race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. The “EEO is the Law” poster is available here.