Danaher Corporation Senior Scientist - Downstream Processing in Portsmouth, United Kingdom
Danaher Company Description
Pall Corporation is a global leader in high-tech filtration, separation, and purification, serving the diverse needs of customers across the broad spectrum of life sciences and industry. Pall Life Sciences provides cutting-edge products and services to meet the demanding needs of customers discovering, developing and producing biotech drugs, vaccines, cell therapies and classic pharmaceuticals. Pall offers advanced medical technologies, which are often a patient’s last line of defense from dangerous pathogens. Pall’s food and beverage products provide critical protection from contaminants during various manufacturing steps. Pall Industrial serves a diverse range of customers in the microelectronics, aerospace, fuels, petrochemical, chemical, automotive, and power generation industries. Pall is a key supplier to the innovative and demanding semiconductor and consumer electronics industries, and provides filtration products used in critical applications on commercial and military aerospace vehicles. Pall products are key to the reliability of industrial equipment. Pall’s engineered solutions help municipal and industrial customers address mounting water quality, scarcity and demand issues, and help energy companies maximize production and develop commercially successful next generation fuels. Headquartered in Port Washington, New York, Pall has offices and plants throughout the world. To learn more about Pall, please visithttps://www.pall.com/en/about-pall.html.
*Position Objective: * * * * Lead the development of manufacturing downstream processes for gene therapy and vaccine applications. * Planning and execution of experiments for Pall downstream process development services including, depth filtration, chromatography, TFF testing, sterile filtration. * Prepare detailed project reports, by combining all data from a specific project from multiple individuals and unit operations.
* Assist the project manager with administrative functions – preparation of report drafts, budget tracking, draft proposals and bill of materials.
Role and Duties: * * * Have extensive knowledge of different unit operations required in the purification of viral vectors, vaccines and monoclonal antibodies. * Advise clients on the best process parameters and consumable choice to deliver maximum recovery of therapeutic product. * Troubleshoot customer data, look for efficiencies and recommend right products and equipment to achieve best results. * Plan and execute experiments for DSP, experience with process development and scale-up of DSP unit-operations. * Having experience with AKTA-systems or other small and large-scale DSP automation systems. * Do some of the required analytic assays, possibly including gels, ELISA, qPCR, SDS-Page. * Analyze project results and summarize for discussion with team. Make recommendations for further optimization. * Help with administrative functions for this project – organize meetings and prepare reports for customers.
•BSc in biological science / chemical engineering and extensive experience in protein purification or MSc in biology / chemical engineering. •Hands on experience in protein purification is essential. •Experience with purification of viral particles (gene therapy and/or vaccine fields) or Monoclonal antibodies. •A good understanding of protein purification mechanisms and basic protein analysis tool (gels, ELISA). •Prior experience compiling information into technical reports.
Danaher Corporation Overview
Danaher is a global science & technology innovator committed to helping our customers solve complex challenges and improve quality of life worldwide. Our world class brands are leaders in some of the most demanding and attractive industries, including life sciences, medical diagnostics, dental, environmental and applied solutions. Our globally diverse team of 71,000 associates is united by a common culture and operating system, the Danaher Business System, which serves as our competitive advantage. We generated $19.9B in revenue last year. We are ranked #162 on the Fortune 500 and our stock has outperformed the S&P 500 by more than 5,200% over 25 years. At Danaher, you can build a career in a way no other company can duplicate. Our brands allow us to offer dynamic careers across multiple industries. We're innovative, fast-paced, results-oriented, and we win. We need talented people to keep winning. Here you'll learn how DBS is used to shape strategy, focus execution, align our people, and create value for customers and shareholders. Come join our winning team. Danaher is committed to competitive compensation that typically has key components including base salary, variable annual incentive compensation based on personal and company performance, and long-term incentive.
Job Function: Science
Primary Location: EMEA-Western Europe-United Kingdom-Hampshire-Portsmouth
Req ID: PAL002978