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Danaher Corporation Scientist II in Sunnyvale, California

Scientist II

Cepheid Location Sunnyvale, California, United States of America

Introduction of the Business:

At Cepheid, we are passionate about improving health care through faster, more accurate diagnostic tests. As a member of our team, you’ll get to make an immediate, measurable impact on a global scale, within an environment that fosters career growth and development. Our mission drives us, every moment of every day, as we develop rapid groundbreaking solutions to solve the world’s most complex health challenges.

Our associates are involved in every stage of molecular diagnostics ­ ­­– from ideation and innovation through development and delivery of life-changing advancements in healthcare-associated infections, sexual health, critical infectious disease, virology and oncology applications. For more details, visit us at www.cepheid.com or follow us on Twitter. (@CepheidNews)

As part of the Danaher family of companies, our work at Cepheid is supported by a global science and technology innovator. In addition to Danaher’s unrivaled leadership training and professional development programs, this relationship also provides expanded career opportunities across industries and brands. Together, we are united by a shared purpose: Helping Realize Life’s Potential.

Responsibilities:

  • Design and develop real time PCR and RT-PCR assays for the GeneXpert platform for detection of microbial pathogens and drug resistance, including primer-probe design, screening and assay optimization.

  • Analyze experimental and field data from on-market and under-development IVD assays and extract and sort large scale datasets to fit into companion data analysis platforms.

  • Develop macros in Microsoft excel to streamline the process of large-scale data import and analysis from GeneXpert platform. May need to work on Python or R-scripts if necessary.

  • Optimize reagent and assay bead formulation for assays in the GeneXpert platform.

  • Clearly understand key scientific principles associated with specific assay development projects and apply independent thought process to assist technical leads to drive projects to completion through different stages.

  • Collaborate with cross-functional teams to collect and collate experimental datasets to determine novel data utilities and applicability.

  • Formulate algorithms for PCR real time and/ or melt based identification for microbial ID and antimicrobial resistance markers.

  • Perform detailed analytical studies required for technical feasibility and design and development phases of complex assays prior to validation phase.

  • Perform analysis of target gene sequences, to identify suitable diagnostic targets, gene mutations, primer/probe binding sites and analyze in-silico inclusivity and exclusivity of DNA/RNA sequences.

  • Handle clinical samples and perform microbiology work of BSL-1 and BSL-2 organisms, including BSL-2 strains.

  • Help develop and write verification and validation SOPs, technical reports, study plan and protocols.

  • Maintain detailed experimental records and electronic laboratory notebooks.

  • Apply analytical problem-solving skills to reagent and system integration issues to identify critical performance factors.

  • Present data at regular internal and external collaborative technical meetings.

  • Allocate time and resources efficiently, effectively prioritize, and continually seek ways to improve individual and corporate efficiency.

  • Be highly goal-oriented and organized and be able to thrive in an atmosphere of shifting demands and priorities.

Minimum Qualifications:

  • MS with 4 to 5 years of experience, or PhD with 0 to 2 years of experience, preferably at a molecular diagnostics company.

  • Strong knowledge on real time PCR assay development, primer and probe design, data analytics and product development is required.

Preferred qualifications:

  • Familiarity with computer programming languages like Python or R with basic proficiency level

  • Advanced level experience with large scale data analysis in Microsoft excel

  • Experience in working in Machine Learning projects

Physical requirements:

  • Ability to work in a research laboratory environment which includes periods of bench-work and working in a bio-safety cabinet

About Danaher

As part of the Danaher family of companies, our work at Cepheid is supported by a global science and technology innovator. In addition to Danaher’s unrivaled leadership training and professional development programs, this relationship also provides expanded career opportunities across industries and brands. Together, we are united by a shared purpose: Helping Realize Life’s Potential.

When you join us, you’ll also be joining Danaher’s global organization, where 69,000 people wake up every day determined to help our customers win. As an associate, you’ll try new things, work hard, and advance your skills with guidance from dedicated leaders, all with the support of powerful Danaher Business System (https://www.danaher.com/how-we-work/danaher-business-system) tools and the stability of a tested organization.Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. We value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes.The EEO posters are available here (https://www.dol.gov/agencies/ofccp/posters) .We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us at 202.419.7762 or applyassistance@danaher.com to request accommodation.If you’ve ever wondered what’s within you, there’s no better time to find out.

Operating Company: Cepheid

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